Caprisil C18-B HPLC High Stability
Caprisil C18-B is highly alkaline deactivated stationary phase with high carbon loading and ultra-high bonding density made by a multi-step. The first step is high-density C18 bonding, and the second step is to produce a highly alkaline deactivated column through a unique multi-end capping process. After testing, C18-B has perfect peak shape and good selectivity. For some samples that are difficult to separate, good results can still be obtained.
▶ High carbon loading and ultra-high bonding density;
▶ Multi-end capping , alkaline deactivation;
▶ High resolution, perfect peak shape.
Chromatographic column: CC553-C18-B, 5 μm, 100 Å, 150 mm × 4.6 mm
Flow rate: 1.0 mL/min
Injection volume: 10 μL
Mobile phase: 0.02 mol/L ammonium formate (pH adjusted to 3.5 with formic acid) : acetonitrile = 68:32
Detector: UV @ 259 nm
Analyte: 1. Argatroban acid
Key Features:
● High carbon loading and ultra-high bonding density•Multi-end capping for alkaline deactivation
● Superior resolution and peak performance
Applications and Compatibility:
Caprisil C18-B columns are chemically similar to Waters Sunfire C18 and Agilent Eclipse XDB-C18
columns, making them a suitable and cost-effective alternative for HPLC analyses that require these chemistries.
Caprisil C18-B/C8-B Columns
Comparison Table
| Feature / Column | Caprisil C18-B | waters Sunfire C18 | Agilent Eclipse XDB-C18 | CaprisilC8-B | Waters Sunfire C8 | Agilent Eclipse XDB-C8 |
| Bonding | High-density C18 | C18 | C18 | C8 | C8 | C8 |
| End-capping | Multi-end, alkalinedeactivated | Standard / high deactivation | XDB / high deactivation | Multi-end, alkalinedeactivated | Standard | XDB |
| Carbon loading | Ultra-high | High | High | High | High | High |
| pH Stability | High (alkalineresistant) | Moderate | High | High | Moderate | High |
| Peak Shape / Resolution | Excellent | Excellent | Excellent | Excellent | Excellent | Excellent |
| Typical Use | RP-HPLC, pharmaceuticals, general analysis | RP-HPLC | RP-HPLC | Moderate hydrophobic analytes | RP-HPLC | RP-HPLC |
| Part Number | Long Description |
| CA533-C18-B | Caprisil C18-B 3μm 100Å 50mm×4.6mm |
| CB533-C18-B | Caprisil C18-B 3μm 100Å 100mm×4.6mm |
| CC533-C18-B | Caprisil C18-B 3μm 100Å 150mm×4.6mm |
| CA553-C18-B | Caprisil C18-B 5μm 100Å 50mm×4.6mm |
| CB553-C18-B | Caprisil C18-B 5μm 100Å 100mm×4.6mm |
| CC553-C18-B | Caprisil C18-B 5μm 100Å 150mm×4.6mm |
| CD553-C18-B | Caprisil C18-B 5μm 100Å 200mm×4.6mm |
| CE553-C18-B | Caprisil C18-B 5μm 100Å 250mm×4.6mm |
Note : we can able to providecustamized columns.

We have individual Technical and R & D Team and worked more than 60 + Experienced Analytical Scientists . we are ready to support Technically before and after sales . For New analytical Method Development or validation, we can able to help to find right columns. our R & D Team can able to provide Customized columns. for more technical information's kindly contact us. morhchem@technicalsuppport.com


