Caprisil C18-P High-Stability Customizable UPLC Column

Caprisil C18-P is specially deactivated to produce superior peak shapes for amines and acids. Caprisil C18-P superior performance is the result of a multistep process beginning with ultra-pure synthetically produced spherical silica. The ultra-pure silica particles are then fully hydroxylated before they undergo an extensive bonding monomeric C18 alkyl chains, using proprietary bonding procedures. The bonded particles are then exhaustively endcapped to react any remaining silanol groups yielding columns that are much more resistant to degradation by acidic and basic mobile phase compositions, while improving peak shapes for amines and acids.

Chromatographic column: Caprisil C18-P 250×4.6mm, 5μm

Mobile phase: 20mM dipotassium hydrogen phosphate (pH =7.6)/methanol (30/70)

Speed: 1 ml/min

Detector: UV 254nm

Injection volume: 10 ul

Samples: gallic acid, p-hydroxybenzoic acid, benzoic acid,Para-methylbenzoic acid

Key Advantages:

❖ Double end-capping technology for improved peak shape and reduced tailing .

❖ Wide pH stability (1.5–10) for enhanced durability and flexibility .

❖ Indicates that this technology is designed to work effectively with basic (alkaline) chemical compounds..

❖ Excellent reproducibility with spherical silica particles .

❖ A technique used to modify or protect reactive end groups, often in polymers or silica-based materials, by capping them with specific reagents.

❖ very suitable for routine analysis.

General Specifications:

Stationary Phase: Octadecylsilyl (C18) or Octylsilyl (C8) bonded silica .

Particle Size: 5 µm (other sizes available on request) .

Pore Size: 100 Å (ideal for small to medium molecules) .

Column Dimensions: (other sizes available on request) .

Inner Diameter (ID): 4.6 mm (standard); also 2.1 mm, 3.0 mm, 10 mm available.

Lengths: 150 mm, 250 mm (standard); 50 mm, 100 mm, 200 mm available .

Endcapping: Double end-capped .

pH Range: 1.5 – 10 .

For Preparative and Customized Columns we will provide based on customer requirements .